abstract：:HPV vaccination schedules have changed as evidence has supported reduced dosing and extended intervals. Women living with HIV (WLWH) represent an important population with no data on alternative dosing. Girls and WLWH received quadrivalent HPV (qHPV) vaccine in a pan-Canadian study of immunogenicity and efficacy. Sero...

journal_title：Vaccine

authors： McClymont E,Ogilvie G,Albert A,Johnston A,Raboud J,Walmsley S,Lipsky N,Loutfy M,Trottier S,Smaill F,Yudin MH,Klein MB,Harris M,Wobeser W,Bitnun A,Kakkar F,Samson L,Brophy J,Karatzios C,Money D,CTN 236 HPV in HIV S

更新日期：2020-03-30 00:00:00

abstract：:Despite a critical need for a respiratory syncytial virus (RSV) vaccine and decades of development efforts, a vaccine to protect infants, elderly, and other at-risk populations from RSV infection remains elusive. We have previously generated a new, live-attenuated vaccine candidate against RSV using rational, computer...

journal_title：Vaccine

authors： Mueller S,Stauft CB,Kalkeri R,Koidei F,Kushnir A,Tasker S,Coleman JR

更新日期：2020-03-23 00:00:00

abstract：:This study investigates the background to low uptake of nasal influenza vaccination in Polish pupils in Edinburgh, Scotland. In autumn 2018, one week after their child's nasal flu vaccination sessions, 365 Polish parents were sent a questionnaire exploring influences on their vaccination choices. The questionnaire inc...

journal_title：Vaccine

authors： Gorman DR,Bielecki K,Larson HJ,Willocks LJ,Craig J,Pollock KG

更新日期：2020-03-17 00:00:00

abstract：BACKGROUND:Maternal immunization with tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine (Tdap) has recently been implemented to prevent infant pertussis. Tdap is still not routinely recommended in Thailand, and there are limited data to support or challenge this strategy. OBJECTIVES:The primar...

journal_title：Vaccine

authors： Sompagdee N,Anuwutnavin S,Phongsamart W,Senawong S,Umrod P,Robkhonburi A

更新日期：2020-03-10 00:00:00

abstract：BACKGROUND:The Bacille Calmette-Guérin (BCG) vaccine against tuberculosis (TB) may have beneficial non-specific effects (NSEs) beyond the protection against TB. This may be related to modifications of the innate immune system. We investigated the effect of BCG at birth on differential white blood cell (WBC) count in he...

journal_title：Vaccine

authors： Jensen SK,Jensen TM,Birk NM,Stensballe LG,Benn CS,Jensen KJ,Pryds O,Jeppesen DL,Nissen TN

更新日期：2020-03-04 00:00:00

abstract：:In this work, we explored the potential of cationic solid lipid nanoparticles (cSLN) as efficient adjuvants for inactivated foot and mouth disease virus (iFMDV) vaccine. The cSLN were prepared by O/W emulsion method with Compritol 888 ATO as lipid matrix, and were modified by cationic lipid Didodecyldimethylammonium b...

journal_title：Vaccine

authors： Li S,Yang Y,Lin X,Li Z,Ma G,Su Z,Zhang S

更新日期：2020-03-04 00:00:00

abstract：:Measles outbreaks occur periodically in remote and difficult to reach areas in countries such as the Democratic Republic of Congo. The possibility to keep measles vaccines at temperatures outside the cold chain for a limited period prior to administration would be an advantage for organizations such as Médecins Sans F...

journal_title：Vaccine

authors： Juan-Giner A,Alsalhani A,Panunzi I,Lambert V,Van Herp M,Gairola S

更新日期：2020-03-04 00:00:00

abstract：:Oral Cholera Vaccine (OCV) has been recognized as an adjunct tool for prevention and control of cholera. However, policy directions are currently unavailable in India to guide the vaccine delivery. We conducted a scoping review to inform the policy about the scopes and challenges of different strategic choices of OCV ...

journal_title：Vaccine

authors： Ray A,Sarkar K,Haldar P,Ghosh R

更新日期：2020-02-29 00:00:00

abstract：:The unique genetic makeup and remarkable competency of Vibrio cholerae are the key factors that help the cholera pathogen adapt rapidly to adverse environmental conditions and resist the detrimental effect of antimicrobial agents. In the last few decades, V. cholerae that causes acute watery diarrhoeal disease cholera...

journal_title：Vaccine

authors： Das B,Verma J,Kumar P,Ghosh A,Ramamurthy T

更新日期：2020-02-29 00:00:00

abstract：:Studies conducted at neonatal intensive care units in Pune, western India, suggested early exposure to rotaviruses and predominance of unusual human-bovine-like G12P[11] strains. The whole genome sequencing and phylogenetic analyses of a naturally attenuated, culture adapted neonatal strain, (NIV-1740121) revealed mul...

journal_title：Vaccine

authors： Ranshing SS,Cherian SS,Agarwal MS,Jagtap AS,Patil CM,Gopalkrishna V

更新日期：2020-02-28 00:00:00

abstract：OBJECTIVE:Despite recommendations by professional organizations that all pregnant women receive inactivated influenza vaccine, safety concerns remain a barrier. Our objective was to assess the effect of trivalent influenza vaccines (IIV3) during pregnancy on parent report 6-month infant development. METHODS:We conduct...

journal_title：Vaccine

authors： Avalos LA,Ferber J,Zerbo O,Naleway AL,Bulkley J,Thompson M,Cragan J,Williams J,Odouli R,Kauffman TL,Ball S,Shifflett P,Li DK

更新日期：2020-02-28 00:00:00

abstract：INTRODUCTION:It is important to quickly identify parent beliefs, intentions, and behaviors toward childhood vaccination, especially parents of children 19 to 35 months. This paper describes parental immunization beliefs, intentions, and behaviors; assesses the relationships between beliefs and intentions regarding chil...

journal_title：Vaccine

authors： Boyle J,Berman L,Nowak GJ,Iachan R,Middleton D,Deng Y

更新日期：2020-02-28 00:00:00

abstract：:The highly pathogenic avian influenza (HPAI) H5N1 viruses and their spillover into the human population pose substantial economic and public health threats. Although antiviral drugs have some effect in treating influenza infection, vaccination is still the most effective intervention to prevent possible pandemic outbr...

journal_title：Vaccine

authors： Lu Y,Landreth S,Liu G,Brownlie R,Gaba A,Littel-van den Hurk SVD,Gerdts V,Zhou Y

更新日期：2020-02-28 00:00:00

abstract：INTRODUCTION:In France, the human papilloma (HPV) vaccine is recommended to all female adolescents, and since 2016 to men having sex with men (MSM) under the age of 27. Here, we aimed to explore HPV vaccine coverage in adult MSM living in France. METHODS:We elaborated an anonymous online questionnaire targeting MSM an...

journal_title：Vaccine

authors： Petit B,Epaulard O

更新日期：2020-02-24 00:00:00

abstract：BACKGROUND:Vaccine hesitancy is a complex behaviour which involves various degrees of indecision about specific vaccines or vaccination uptake. Access to antenatal care had been associated with positive vaccine behavior. OBJECTIVE:To determine the prevalence of vaccine hesitancy towards childhood immunisation amongst ...

journal_title：Vaccine

authors： Kalok A,Loh SYE,Chew KT,Abdul Aziz NH,Shah SA,Ahmad S,Mohamed Ismail NA,Abdullah Mahdy Z

更新日期：2020-02-24 00:00:00

abstract：BACKGROUND:Vaccination coverage in Bosnia and Herzegovina has been declining over recent years. A World Health Organization Tailoring Immunization Programmes (TIP) project is underway to gain insights into the underlying reasons for this, to develop tailored interventions. As part of TIP, this study aimed to investigat...

journal_title：Vaccine

authors： Musa S,Skrijelj V,Kulo A,Habersaat KB,Smjecanin M,Primorac E,Becirovic D,Jackson C

更新日期：2020-02-18 00:00:00

abstract：:Enterovirus type 71 (EV71) and coxsackievirus A 16 (CA16) are recognized as the major pathogens responsible for human hand-foot-mouth disease. To develop a bivalent EV71-CA16 vaccine, rhesus macaques immunized with two doses of this vaccine via the intradermal route were challenged with EV71 or CA16, and their clinica...

journal_title：Vaccine

authors： Fan S,Liao Y,Jiang G,Jiang L,Wang L,Xu X,Feng M,Yang E,Zhang Y,Cui W,Li Q

更新日期：2020-02-18 00:00:00

abstract：BACKGROUND:Racial differences have been observed in the rate of bacterial infection and disease progression in HIV. Here, we evaluate racial differences in seasonal influenza vaccine responses. METHODS:16 healthy controls (9 Caucasians (CC) and 7 African Americans (AA)) and 26 antiretroviral therapy (ART)-treated avir...

journal_title：Vaccine

authors： Ma P,Luo Z,Qian J,Yan Z,Zhang L,Martin L,Wang Z,Xia H,Yu F,Jiang W

更新日期：2020-02-18 00:00:00

abstract：:Vaccines are everywhere hugely successful but are also under attack. The reason for the latter is the perception by some people that vaccines are unsafe. However that may be, vaccine safety, life any other scientific subject, must be constantly studied. It was from this point of view that a meeting was organized at th...

journal_title：Vaccine

authors： Plotkin SA,Offit PA,DeStefano F,Larson HJ,Arora NK,Zuber PLF,Fombonne E,Sejvar J,Lambert PH,Hviid A,Halsey N,Garçon N,Peden K,Pollard AJ,Markowitz LE,Glanz J

更新日期：2020-02-18 00:00:00

abstract：:Japanese encephalitis (JE) is the most important cause of acute encephalitis syndrome (AES). Japanese encephalitis virus (JEV), the prototype member of the JE serocomplex, belongs to the genus Flavivirus. The immunogenic proteins envelope (E) and non-structural protein 1 (NS1) of JEV are widely explored for the develo...

journal_title：Vaccine

authors： Nath B,Vandna,Saini HM,Prasad M,Kumar S

更新日期：2020-02-11 00:00:00

abstract：BACKGROUND:Immunization programs' resilience to shocks is central to their success, but little empirical evidence documents resilience in action. We sought to characterize the decline of HPV vaccination in Denmark after negative media coverage and recovery during a national information campaign. METHODS:We conducted a...

journal_title：Vaccine

authors： Hansen PR,Schmidtblaicher M,Brewer NT

更新日期：2020-02-11 00:00:00

abstract：BACKGROUND:PCV13 (conjugated polysaccharide) and PPSV23 (polysaccharide only) are two licensed vaccines targeting S. pneumoniae. The role of CD4 T-cell responses in pneumococcal vaccines among healthy participants and their impact on antibodies is not yet known. METHODS:Ten adults (5 old and 5 young) received PCV13 (p...

journal_title：Vaccine

authors： Sterrett S,Peng BJ,Burton RL,LaFon DC,Westfall AO,Singh S,Pride M,Anderson AS,Ippolito GC,Schroeder HW Jr,Nahm MH,Krishna Prasad A,Goepfert P,Bansal A

更新日期：2020-02-11 00:00:00

abstract：BACKGROUND:Streptococcus pyogenes (group A Streptococcus, Strep A) is a widespread pathogen that continues to pose a significant threat to human health. The development of a Strep A vaccine remains an unmet global health need. One of the major vaccine strategies is the use of M protein, which is a primary virulence det...

journal_title：Vaccine

authors： Pastural É,McNeil SA,MacKinnon-Cameron D,Ye L,Langley JM,Stewart R,Martin LH,Hurley GJ,Salehi S,Penfound TA,Halperin S,Dale JB

更新日期：2020-02-05 00:00:00

abstract：:This paper analyses farmers' behavioural responses to Government attempts to reduce the risk of disease transmission from badgers to cattle through badger vaccination. Evidence for two opposing behavioural adaptions is examined in response to the vaccination of badgers to reduce the risk of transmission to farmed catt...

journal_title：Vaccine

authors： Enticott G,Maye D,Naylor R,Brunton L,Downs SH,Donnelly CA

更新日期：2020-01-29 00:00:00

abstract：INTRODUCTION:Implementation of the 7-valent pneumococcal conjugate vaccine (PCV7) in infant vaccination programs has substantially reduced the burden of PCV7 serotypes also in adult community-acquired pneumonia (CAP). Currently, it is unclear, if this extensive herd protection effect can be extrapolated to the addition...

journal_title：Vaccine

authors： Forstner C,Kolditz M,Kesselmeier M,Ewig S,Rohde G,Barten-Neiner G,Rupp J,Witzenrath M,Welte T,Pletz MW,CAPNETZ study group.

更新日期：2020-01-29 00:00:00

abstract：:Domestic dogs constitute the main reservoir of Leishmania infantum and play a key role in transmission to humans. The main tool for controlling infection spread is a safe and effective vaccine, as successful immunization of dogs could significantly reduce the incidence of human visceral leishmaniosis (VL) and is the m...

journal_title：Vaccine

authors： Cacheiro-Llaguno C,Parody N,Renshaw-Calderón A,Osuna C,Alonso C,Carnés J

更新日期：2020-01-22 00:00:00

abstract：BACKGROUND:We have previously developed a recombinant avian avulavirus serotype 10 (rAAvV-10/HA) expressing the hemagglutinin (HA) gene of a highly pathogenic avian influenza virus (HPAIV) as an emergency vaccine for poultry. rAAvV-10/HA can overcome the activity of the anti-AAvV-1 (Newcastle disease virus) antibody ac...

journal_title：Vaccine

authors： Tsunekuni R,Tanikawa T,Nakaya T,Saito T

更新日期：2020-01-22 00:00:00

abstract：:First year medical students at an allopathic medical school regional campus were asked to complete a 10-question survey at both the beginning and the conclusion of a required course on immunology, hematology and oncology. The survey was designed to solicit student attitudes about vaccination and the students' level of...

journal_title：Vaccine

authors： Onello E,Friedrichsen S,Krafts K,Simmons G Jr,Diebel K

更新日期：2020-01-22 00:00:00

abstract：:Duck Tembusu virus (TMUV) is an emerging pathogenic flavivirus that causes severe egg-drop and fatal encephalitis in domestic ducks and geese. Although a live-attenuated virus vaccine is effective for disease control, the stability of the attenuation has not been clearly evaluated due to a poor understanding of the at...

journal_title：Vaccine

authors： Zhang L,Sun M,Zhang Q,Wang J,Cao Y,Cui S,Su J

更新日期：2020-01-22 00:00:00

abstract：BACKGROUND:This phase I trial evaluated the safety and immunogenicity of a candidate tuberculosis vaccination regimen, ChAdOx1 85A prime-MVA85A boost, previously demonstrated to be protective in animal studies, in healthy UK adults. METHODS:We enrolled 42 healthy, BCG-vaccinated adults into 4 groups: low dose Starter ...

journal_title：Vaccine

authors： Wilkie M,Satti I,Minhinnick A,Harris S,Riste M,Ramon RL,Sheehan S,Thomas ZM,Wright D,Stockdale L,Hamidi A,O'Shea MK,Dwivedi K,Behrens HM,Davenne T,Morton J,Vermaak S,Lawrie A,Moss P,McShane H

更新日期：2020-01-22 00:00:00

abstract：INTRODUCTION:Despite the enormous benefits of childhood and maternal immunisation to individual and population health, the uptake of maternal vaccines during pregnancy remains suboptimal. Midwives are a trusted information source for parents and play an important role in the provision of immunisation information. Under...

journal_title：Vaccine

authors： Frawley JE,McKenzie K,Sinclair L,Cummins A,Wardle J,Hall H

更新日期：2020-01-10 00:00:00

abstract：BACKGROUND:Cervical cancer is one of the most prevalent cancers in women caused by the human papillomavirus (HPV) that leads to a substantial disease burden for health systems. Prevention through vaccination can significantly reduce the prevalence of cervical cancer. The objective of this study is to evaluate the poten...

journal_title：Vaccine

authors： Mahumud RA,Gow J,Alam K,Keramat SA,Hossain MG,Sultana M,Sarker AR,Islam SMS

更新日期：2020-01-10 00:00:00

abstract：INTRODUCTION:Adolescents and young adults are at a high risk of developing human papillomavirus (HPV) infections, which can be prevented with the use of vaccines. Moreover, a combined immunization strategy for administration of HPV vaccines with other routine vaccines may lead to better compliance. We aim to comprehens...

journal_title：Vaccine

authors： Li Y,Zhu P,Wu M,Zhang Y,Li L

更新日期：2020-01-10 00:00:00

abstract：:Measles has been reemerging in South Korea since December 2018 resulting in 185 cases by September 2019. We calculated contact-adjusted immunity levels against measles in South Korea using national seroprevalence data in 2014, vaccination uptake rates, and an age-specific contact matrix. We further explored options to...

journal_title：Vaccine

authors： Chun JY,Park WB,Kim NJ,Choi EH,Funk S,Oh MD

更新日期：2020-01-10 00:00:00

abstract：BACKGROUND:To support vaccine decision-making we estimated from the societal perspective the potential health impact and costs averted through immunization with three vaccines - Haemophilus influenzae type b (Hib), pneumococcal conjugate vaccine (PCV) and rotavirus vaccine (RVV). METHODS:Based on variability in diseas...

journal_title：Vaccine

authors： Constenla D,Liu T

更新日期：2019-12-10 00:00:00

abstract：:The carbohydrate moieties on HIV-1 envelope glycoprotein (Env) act as shields to mask conserved neutralizing epitopes, while the hyperimmunogenic variable regions are immunodominant in inducing non-neutralizing antibodies, representing the major challenge for using Env as a vaccine candidate to induce broadly neutrali...

journal_title：Vaccine

authors： Fu M,Hu K,Hu H,Ni F,Du T,Shattock RJ,Hu Q

更新日期：2019-12-03 00:00:00

abstract：BACKGROUND:Native American populations experience a substantial burden of pneumococcal disease despite use of highly effective pneumococcal conjugate vaccines (PCVs). Protein-based pneumococcal vaccines may extend protection beyond the serotype-specific protection elicited by PCVs. METHODS:In this phase IIb, double-bl...

journal_title：Vaccine

authors： Hammitt LL,Campbell JC,Borys D,Weatherholtz RC,Reid R,Goklish N,Moulton LH,Traskine M,Song Y,Swinnen K,Santosham M,O'Brien KL

更新日期：2019-12-03 00:00:00

abstract：:Rabies is an ancient zoonosis that continues to be an important health problem worldwide. Vaccination with rabies vaccine is the most important strategy to prevent rabies. Adjuvants contribute to the immune response of viral vaccine. The aim of this study was to investigate whether artemisinin derivatives artesunate a...

journal_title：Vaccine

authors： Luo J,Zhang Y,He H,Liu Q,Huang S,Guo X

更新日期：2019-12-03 00:00:00

abstract：:There is a growing public health interest in controlling sexually transmitted infections (STIs) through vaccination due to increasing recognition of the global disease burden of STIs and the role of STIs in women's reproductive health, adverse pregnancy outcomes, and the health and well-being of neonates. Neisseria go...

journal_title：Vaccine

authors： Vincent LR,Jerse AE

更新日期：2019-11-28 00:00:00

abstract：:On 1 February 2016, in the context of the ongoing Zika virus epidemic, the WHO declared that the recently reported clusters of microcephaly and other neurological disorders constituted a Public Health Emergency of International Concern (PHEIC). In response, WHO in collaboration with UNICEF and a working group of indep...

journal_title：Vaccine

authors： Vannice KS,Giersing BK,Kaslow DC,Griffiths E,Meyer H,Barrett A,Durbin AP,Wood D,Hombach J

更新日期：2019-11-28 00:00:00